| Fairmont Hotels and Resorts | Toronto | 1907 |
| Fandango | Los Ángeles | 2000 |
| Farmers Insurance Group | Wilshire Boulevard, Los Ángeles | 1928 |
| Fastenal | Winona | 1967 |
| Fastly | San Francisco | 2011 |
| Feastables | Chicago | abril 2021 |
| Federal Home Loan Banks | Boston, Chicago, Pittsburgh, Dallas, Atlanta, Des Moines, Topeka, Cincinnati, Nueva York, San Francisco, Indianápolis | 1932 |
| FEI Company | Hillsboro | 1971 |
| Fenway Sports Group | Boston | 2001 |
| Ferrocarril del Pacífico Norte | Saint Paul | 2 de julio de 1864 |
| FireEye | Milpitas | febrero 2004 |
| First Citizens BancShares | Raleigh | 7 de agosto de 1986 |
| First Data | Atlanta | 1969 |
| FIS (empresa) | — | 1 de febrero de 2006 |
| Fitbit | San Francisco | 2007 |
| Flex LTD | San José, Singapur | 1969 |
| Florsheim Shoes | Glendale | 1892 |
| FMC Technologies | Houston | 2000 |
| Fodera | Nueva York | 1983 |
| Folgers | Nueva Orleans | 1850 |
| Forrester | Cambridge | 1983 |
| Fortinet | Sunnyvale | 2000 |
| Fortune Brands | Deerfield | 1969 |
| Fossil | Richardson | 1984 |
| Fox Atomic | — | 2006 |
| Fox Sports | Los Ángeles | 12 de agosto de 1994 |
| Fresh Del Monte Produce | Coral Gables | 1886 |
| Frito-Lay | Plano | 1961 |
| Frontier Airlines | Denver | 1994 |
| Fruit of the Loom | Bowling Green | 1851 |
| Fry's Electronics | San José | 1985 |
| Future Shop | Burnaby | 1982 |
| Gaikai | Aliso Viejo | noviembre 2008 |
| Gannett | Tysons, Nueva York | 6 de octubre de 1906 |
| Gathering of Developers | Texas | enero 1998 |
| GE Aerospace | Evendale | 15 de abril de 1892 |
| Genentech | South San Francisco | 7 de abril de 1976 |
| General Motors | Detroit | 16 de septiembre de 1908 |
| Genesys | Daly City | 1990 |
| GEO Group | Boca Raton | 1984 |
| GeoEye | Herndon | 1992 |
| Gerber Legendary Blades | Tigard | 1939 |
| Getty Oil | East Meadow | 1964 |
| Gilead Sciences | Foster City | junio 1987 |
| Global Electric Motorcars | Fargo | 1992 |
| Global Gillette | Boston | 28 de septiembre de 1901 |
| Global Infrastructure Partners | Nueva York | mayo 2006 |
| GMT Games | Hanford | 1990 |