| Office Depot | Boca Raton | 1986 |
| ON Semiconductor | Scottsdale | 18 de junio de 1992 |
| Orbcomm | Fort Lee | 1993 |
| Orbital Sciences Corporation | Dulles | 1982 |
| OTC Markets Group | Nueva York | 1913 |
| Owen illinois | Toledo, Perrysburg | 1903 |
| Panera Bread | Sunset Hills | 1987 |
| Peabody Energy | San Luis | 1883 |
| PepsiCo | Purchase | 1961 |
| Plantronics | Santa Cruz | 1961 |
| Plug Power | Latham, Slingerlands | 1997 |
| PNC Financial Services | One PNC Plaza | 1982 |
| Polycom | San José | 1990 |
| Principal Financial Group | Des Moines | 1879 |
| Prudential Financial | Sede de Prudential | 1875 |
| Qlikview | King of Prussia | 1993 |
| Qorvo | Greensboro | 2015 |
| Rackspace | — | 1998 |
| Raytheon Technologies Corporation | condado de Arlington | 3 de abril de 2020 |
| Razer Inc. | George Town, Singapur, Carlsbad, Irvine, San Francisco | 1998 |
| Realty income | San Diego | 1969 |
| Regeneron Pharmaceuticals | Eastview | 1988 |
| Rite Aid | Filadelfia, Municipio de East Pennsboro (condado de Cumberland, Pensilvania) | 1962 |
| Rockwell Collins | Cedar Rapids | 1933 |
| Rocky Mountain Chocolate | Durango | 1981 |
| Ross Stores | Dublin | 1954 |
| RR Donnelley | Chicago | 1864 |
| Ryder | Coral Gables | 1933 |
| S&P Global | Rockefeller Center, Nueva York | — |
| Sanmina-SCI Corporation | San José | 1980 |
| Scholastic Corporation | Nueva York, Scholastic Building | 1920 |
| Seagate | Cupertino | 1979 |
| Sealy Corporation | Trinity | 1881 |
| Sears | Hoffman Estates | 1892 |
| Sears Holdings Corporation | Hoffman Estates | 2005 |
| Similarweb | Guivatayim | 2007 |
| Sinclair Broadcast Group | Hunt Valley, Cockeysville, Union Valley | 1971 |
| Sirius XM Radio | Nueva York | 29 de julio de 2008 |
| Six Flags | Arlington | 1961 |
| Skullcandy | Park City | 2003 |
| Slack Technologies | San Francisco | 2009 |
| Smith & Wesson | Springfield | 1852 |
| Snap-on | Kenosha | 1920 |
| Snowflake Inc. | San Mateo | 2012 |
| SoFi | San Francisco | 26 de abril de 2011 |
| SoundHound | Santa Clara | septiembre 2005 |
| Southern Company | Atlanta | 1945 |
| SpaceX | Starbase | 14 de marzo de 2002 |